Insights into Antibiotic Resistance Through Metagenomic Approaches

Robert Schmieder; Robert Edwards


Future Microbiol. 2012;7(1):73-89. 

In This Article

Antibiotic Resistance in Microbial Communities

Antibiotics are widely used in the clinical setting to treat a range of diseases, and recent studies are directed at understanding the impacts of those treatments on the human microbiota. In addition, antibiotics are used in agricultural settings, and the impact of those treatments on human health is controversial. In the next sections we discuss the identification of antibiotic resistance genes and their impact on human health; the isolation of antibiotic resistance genes from the environment and the implications for the evolution of new resistance mechanisms; and how the agricultural use of antibiotics may influence both human health and resistance evolution.