Challenge of Evidence in Individualized Medicine

Kathleen Kraft; Wolfgang Hoffmann

Disclosures

Personalized Medicine. 2012;9(1):65-71. 

In This Article

Abstract and Introduction

Abstract

Tension between standardization and individualization has always been a characteristic of medical activity. However, whether it is better that interventions should be based on guideline recommendations on the basis of large multicenter trials, or on a genetic biomarker in individualized medicine, can be the subject of debate. With the aid of stratification, evidence-based medicine and individualized medicine could be linked. Networks of large research projects, involving clinical, biomedical, molecular and other expertises are necessary for evidence-based evaluation, standardization, and clinical validation of new methods and algorithms.

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