Comparative Effectiveness Research for Prostate Cancer Radiation Therapy

Current Status and Future Directions

Xinglei Shen; Nicholas G Zaorsky; Mark V Mishra; Kathleen A Foley; Terry Hyslop; Sarah Hegarty; Laura T Pizzi; Adam P Dicker; Timothy N Showalter


Future Oncol. 2012;8(1):37-54. 

In This Article

Abstract and Introduction


Comparative effectiveness research aims to help clinicians, patients and policymakers make informed treatment decisions under real-world conditions. Prostate cancer patients have multiple treatment options, including active surveillance, androgen deprivation therapy, surgery and multiple modalities of radiation therapy. Technological innovations in radiation therapy for prostate cancer have been rapidly adopted into clinical practice despite relatively limited evidence for effectiveness showing the benefit for one modality over another. Comparative effectiveness research has become an essential component of prostate cancer research to help define the benefits, risks and effectiveness of the different radiation therapy modalities currently in use for prostate cancer treatment.


Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.