Top 10 Critical Care Articles: 2011

Marrecca Fiore


December 08, 2011

In This Article


Sepsis, septic shock, fluid therapy, and the DRESS syndrome were among the topics that dominated the headlines of the most read articles by intensivists in 2011.

Articles focused on clinical therapies to treat sepsis and septic shock were the most popular among Medscape's Critical Care members, as were articles that focused on markers of increased mortality in these extremely complex conditions.

Here is a list of the most popular articles of the year. If you haven't read them, please consider taking some time now to do so.

The Top 10 Most Read Articles by Intensivists

10. High-Flow Oxygen Cuts Need for Intubation in Acute Respiratory Failure
High-flow oxygen therapy reduces the need for intubation and is an effective alternative to bilevel positive airway pressure in older children and adults with acute respiratory failure.

9. What Is the Best Treatment for Septic Shock?
Robert Glatter, MD, gives his thoughts on treating this condition.

8. New Brain Death Guidelines for Children Released
A task force has updated the brain death guidelines for the first time in nearly 25 years.

7. Inappropriate Antibiotic Therapy in Gram-Negative Sepsis Increases Hospital Length of Stay
Gram-negative severe sepsis and septic shock treatment protocol changes could lead to improved outcomes and cost savings.

6. High-Dose Dexmedetomidine for Sedation in the Intensive Care Unit
This centrally acting agent causes sedation without respiratory depression.

5. Hemodynamic Parameters to Guide Fluid Therapy
Determining intravascular volume can be extremely difficult in critically ill and injured patients as well as those undergoing major surgery.

4. Corticosteroid Therapy for Patients in Septic Shock
Improve your understanding of the mechanisms for adrenocortical insufficiency during sepsis.

3. Sepsis Drug Xigris Pulled From Worldwide Market
Physicians should stop ongoing treatment with Xigris now that it has failed a new efficacy test, according to the US Food and Drug Administration (FDA).

2. The DRESS Syndrome: The Great Clinical Mimicker
A research article that looks at this complex syndrome as observed in the case of a 44-year-old woman.

Keep reading for the number one article plus a few runners up.


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