Bacterial Type I Signal Peptidases as Antibiotic Targets

Smitha Rao CV; Jozef Anné


Future Microbiol. 2011;6(11):1279-1296. 

In This Article


The latest crystal structure data reveals that contrary to previous conclusions, glycosylation does not interfere with antibiotic activity of arylomycin and that such modifications might be used to further optimize the pharmacokinetic properties of the molecule.[82]


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