The Diagnosis and Management of Lymphocytic Hypophysitis

Sherry L Iuliano; Edward R Laws

Disclosures

Expert Rev Endocrinol Metab. 2011;6(6):777-783. 

In This Article

Five-year View

The most recent changes in this condition include the recognition that this disorder can occur in both women and men, that it is not necessarily provoked by pregnancy, and that it can be present associated with a variety of autoimmune-type problems such as IgG4-related hypophysitis[5] and CTLA-4 blockade related to hypophysitis.[3] These clues to the etiology of this unique disease entity will undoubtedly expand. At present, the treatment and the indications for surgery are unlikely to change. The essential roles of steroid therapy, and debulking with surgery for expanding sellar masses unresponsive to medical management, are likely to remain unchanged.

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