Contemporary Management of Raynaud's Phenomenon and Digital Ischaemic Complications

Ariane L. Herrick


Curr Opin Rheumatol. 2011;23(6):555-561. 

In This Article


Key recent advances have been the increased understanding of the role of phosphodiesterase inhibitors and of ET-1 receptor antagonists (both of which are now widely used in patients with severe disease), the revisiting of topical GTN, and the increased recognition that optimal management of patients with ischaemic complications includes close liaison with surgical colleagues: timely surgical debridement or digital sympathectomy may save a digit. These advances have been driven by increased networking of clinicians internationally, facilitating much larger clinical trials than have previously been possible, and offering the potential of successfully addressing the remaining unanswered questions.


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