A.R. Shipman; G.W.M. Millington

Disclosures

The British Journal of Dermatology. 2011;165(4):743-750. 

In This Article

Obesity, Diabetes Mellitus and the Skin

Obesity is associated with insulin resistance and type 2 diabetes mellitus.[2,66,67] Therefore, there is a secondary association of obesity with all the cutaneous associations of diabetes mellitus (see Table 1).[2,66,67] Specific dermatological associations with diabetes and obesity would include fibroepithelial polyps, acanthosis nigricans and acne keloidalis nuchae,[7,22,68,69] although acanthosis nigricans can also be familial or associated with malignancies[70,71] and some consider fibroepithelial polyps to be associated with diabetes alone, in the absence of obesity.[72] On the other hand, fibroepithelial polyps express increased amounts of leptin and mast cells, which might favour a link with obesity, via an altered adipocytokine environment.[13,14,27,28,57]

Comments

3090D553-9492-4563-8681-AD288FA52ACE
Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.
Post as:

processing....