A.R. Shipman; G.W.M. Millington

Disclosures

The British Journal of Dermatology. 2011;165(4):743-750. 

In This Article

Obesity and Atopic Eczema

Obesity has been shown to alter the inflammatory state of an individual, leading to a low-level chronic inflammatory response and IL-6 secretion.[90] There is an association between obesity, asthma and atopic eczema.[8,91,92] Mast cells can be synthesized from WAT,[14] increased leptin levels correlate with allergen sensitization[93,94] and obesity correlates with skin infections.[7,83] All these observations could perhaps provide part of the pathogenic link between increased BMI and atopic eczema.

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