Pathophysiology of Itch and New Treatments

Ulrike Raap; Sonja Ständer; Martin Metz


Curr Opin Allergy Clin Immunol. 2011;11(5):420-427. 

In This Article


Chronic itch is a common problem, which can severely impair the quality of life of affected patients. In the skin and nervous system, complex cellular interactions have a pivotal impact on the pathophysiology of itch. Thus, knowledge of the underlying mechanisms will help us to identify novel treatment strategies, which is displayed by small case series of promising drugs and needs to be further supported by randomized trials.


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