Reducing Mortality in Severe Sepsis and Septic Shock

Andrew T. Levinson, M.D., M.P.H.; Brian P. Casserly, M.D.; Mitchell M. Levy, M.D.


Semin Respir Crit Care Med. 2011;32(2):195-205. 

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Although no studies show decreased mortality with a positive culture diagnosis of a pathogen, the SSC recommends at least two sets of blood cultures from two different sites, as well as any other potential source of infection, including indwelling catheters, tissues, and body fluids. Cultures should be drawn prior to beginning antimicrobial therapy to aid treatment and to narrow antibiotic coverage.[14,15]


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