Reducing Mortality in Severe Sepsis and Septic Shock

Andrew T. Levinson, M.D., M.P.H.; Brian P. Casserly, M.D.; Mitchell M. Levy, M.D.


Semin Respir Crit Care Med. 2011;32(2):195-205. 

In This Article


Sepsis remains one of the leading causes of mortality in critically ill patients in the ICU. Over the last decade there has been a demonstrable significant reduction in mortality from severe sepsis and septic shock through the use of performance metrics and collaborative quality improvement efforts that facilitate the incorporation of the latest scientific and clinical advancements into bedside practice. As our scientific knowledge and clinical expertise continue to grow as to the treatment of patients with sepsis, and new innovative technologies and approaches are developed, continued efforts must be made to translate this into improved patient care.


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