Alternative Hair-dye Products for Persons Allergic to Para-phenylenediamine

Andrew Scheman; Christina Cha; Manpreet Bhinder


Dermatitis. 2011;22(4) 

In This Article

Objective and Methods

In this study, we examined whether it is likely that individuals allergic to PPD will be able to tolerate hair-dye products containing PTDS.

We performed a retrospective analysis of all patchtested patients seen in a busy patch-testing center from October 2006 through October 2010. During that time, 28 patients found to be allergic by patch tests with PPD were tested with a hair dye series recommended in the literature to determine if they were also allergic to other ingredients found in hair-dye products;[3] the substances tested are listed in Table 1. In addition, during January 2004 through October 2006, seven additional patients who had positive patch-test reactions to PPD were tested with PTDS but not to the rest of the hair dye series listed in Table 1.

Starting in January 2008, any patient who had a positive patch-test reaction to PPD and negative patch-test reactions to PTDS and the rest of the hair dye series were advised to use one of the new PPD-free PTDS-based hairdye products. These 13 patients were then contacted to determine if they had tolerated the recommended products.


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