Individualizing Hormone Therapy to Minimize Risk

Accurate Assessment of Risks and Benefits

Donna Shoupe


Women's Health. 2011;7(4):475-485. 

In This Article

Benefits of Estrogen Treatment if Started Within a Therapeutic Window

As with the risk profile, the age of initiation plays a large part in maximizing the benefit profile. There is a therapeutic window where estrogen therapy is optimal. After many years of estrogen deficiency, the tissue changes may be advanced and the benefit of estrogen may be dramatically reduced. The primary beneficial action of estrogen is in prevention, that is protecting healthy tissue (Box 5).


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