Sexual Transmission of Hepatitis C Virus Among HIV-Infected Men Who Have Sex With Men

New York City, 2005-2010

Daniel S. Fierer, MD; Stephanie H. Factor, MD; Alison J. Uriel, MBBS; Damaris C. Carriero, MS; Douglas T. Dieterich, MD; Michael P. Mullen, MD; Arielle Klepper, Wouter van Seggelen, MSc; Kathryn Childs, MBBS; Andrea D. Branch, PhD; Deborah Holtzman, PhD; John W. Ward, MD; Yury Khudyakov, PhD; Scott D. Holmberg, MD


Morbidity and Mortality Weekly Report. 2011;60(28):945-950. 

In This Article

Results of Phylogenetic Analyses

Polymerase chain reaction and sequencing of a 470 base-pair region of NS5B from HCV strains recovered from 50 of the 74 men were conducted using methods described previously.[4] Forty-seven of the 50 were genotype 1a, and three were genotype 1b. A maximum-likelihood phylogenetic tree was then created.[5]* These analyses identified five clusters of closely related HCV variants from 26 (55%) of the 47 men with genotype 1a infections.


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