Can Nicotine be Used Medicinally in Parkinson's Disease?

Claire Thiriez; Gabriel Villafane; Frédérique Grapin; Gilles Fenelon; Philippe Remy; Pierre Cesaro

Disclosures

Expert Rev Clin Pharmacol. 2011;4(4):429-436. 

In This Article

Expert Commentary

There is little solid clinical evidence to date regarding nicotine use in PD patients and the evidence that exists is inconclusive at best. However, given the preclinical data and the limitations in the clinical studies already performed, further work is required to fully answer the question. The ongoing trials address different targets: improvement of motor symptoms or complications, impulse control disorders and neuroprotection. A recent public release from Neuraltus Inc. support an antidyskinetic effect.[101] Moreover, the method of administration and dose have still not been clearly established.

Comments

3090D553-9492-4563-8681-AD288FA52ACE
Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.
Post as:

processing....