Antioxidant and Antiatherogenic Effects of Pomegranate

Stacy L. Haber, Pharm.D; Jamie K. Joy, Pharm.D; Roxanne Largent, Pharm.D


Am J Health Syst Pharm. 2011;68(14):1302-1305. 

In This Article

Adverse Effects

The high levels of tannin in pomegranate may cause gastric irritation, and one study found a significant weight gain in patients who received a pomegranate supplement.[2,6] Six publications described a total of 11 patients who developed allergic reactions, including pruritus, urticaria, angioedema, rhinorrhea, bronchospasm, dyspnea, and red itchy eyes, after ingesting pomegranate fruit.[13,14,15,16,17,18] One case report described contact urticaria syndrome of the allergic type in a woman who had been working with pomegranate seeds during the preparation of a meal.[19]


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