Economic Impact of Venous Thromboembolism After Hip and Knee Arthroplasty

Potential Impact of Rivaroxaban

Richard J Friedman; Nishan Sengupta; Michael Lees


Expert Rev Pharmacoeconomics Outcomes Res. 2011;11(3):299-306. 

In This Article

Economic Impact of VTE

A number of studies have estimated the economic burden of VTE,[33–37] and it has been noted that any type of prophylaxis saves costs compared with no prophylaxis.[38] The costs of DVT were found to vary depending on the occurrence of complications. One study found that the mean 6-month treatment costs for inpatient management ranged from US$3906 to US$17,168, depending on complication status.[39] For outpatient management in the 6 months after DVT, costs ranged from US$2394 to US$3369, depending on the frequency of LMWH injection and the need for professional assistance.[39] However, compared with warfarin, extended prophylaxis with LMWH has been found to be cost effective.[40] Studies of the economic consequences of VTE after major orthopedic surgery have yielded a number of estimates.[41] A study using data from a large healthcare claims database calculated much higher in-hospital mean billed charges for the index admission after THA: US$36,705 in patients with no VTE, US$62,558 in patients with in-hospital VTE and US$34,970 for a post-discharge VTE.[42] Similarly, costs after TKA were US$35,601 in patients with no VTE, US$44,898 in patients with in-hospital VTE and US$31,774 for a post-discharge VTE.[42]


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