Duration of Thromboprophylaxis After Total Hip & Knee Arthroplasty
An early recommendation for patients undergoing THA was to extend the use of LMWHs beyond hospital discharge, particularly with the shift towards reduced duration of hospitalization after THA and TKA (mean 3.7 days). More recently, the American College of Chest Physicians (ACCP) guidelines recommend LMWHs, fondaparinux or warfarin for at least 10 days and up to 35 days after THA, and suggest extended thromboprophylaxis up to 35 days after TKA in certain patients. There is increasing evidence that the risk of VTE remains for some time after THA[15,16] and, to a lesser extent, after TKA, and also that extended prophylaxis after surgery may significantly reduce the frequency of DVT.[18–20]
Expert Rev Pharmacoeconomics Outcomes Res. 2011;11(3):299-306. © 2011 Expert Reviews Ltd.
Cite this: Economic Impact of Venous Thromboembolism After Hip and Knee Arthroplasty - Medscape - Jun 01, 2011.