Propylene Glycol

An Often Unrecognized Cause of Allergic Contact Dermatitis in Patients Using Topical Corticosteroids

Mohammed Al Jasser, MD; Nino Mebuke; Gillian de Gannes, MD, FRCPC


Skin Therapy Letter. 2011;16(5) 

In This Article

Sources of PG

Approximately half of the PG produced is used in the synthesis of other chemicals.[2] The other half is utilized in the manufacturing of many industrial and personal care products. PG is used as a plasticizer, solvent (in lacquers and varnishes), and as a component in antifreeze products, lubricants, cutting-fluids, and inks. It is found in many cosmetic and pharmaceutical preparations, food (for coloring, thickening, and flavoring), and household cleansers. In a recent study by the North American Contact Dermatitis Group (NACDG), personal care products were found to be the most common sources of exposure to PG (53.8%), followed by topical steroids, and other topical medicaments.[3]


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