Stress as an Influencing Factor in Psoriasis

Misha M. Heller, BA; Eric S. Lee, BS; John Y.M. Koo, MD


Skin Therapy Letter. 2011;16(5) 

In This Article


An extensive number of clinical studies exists supporting stress as an exacerbating factor in psoriasis.[5–12] One problem is that most investigations on stress are generally retrospective, primarily based on patient recall of past events, which may or may not be an entirely reliable measure. However, there are three prospective studies confirming an association between stress and psoriasis.[4,10]

In sum, stress appears to be an important precipitating factor in the development and exacerbation of psoriasis. Patients who are identified as stress responders may especially benefit from stress reduction through psychotherapy and/or pharmacotherapy.


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