Kirsi M. Järvinen


Curr Opin Allergy Clin Immunol. 2011;11(3):255-261. 

In This Article

How to Manage a Food-induced Anaphylactic Reaction?

The mainstay of treatment of any anaphylactic reaction is the timely administration of epinephrine. Various reports on food-induced anaphylaxis occurring in the community have identified underutilization of epinephrine. Epinephrine was administered in 25–44% of severe reactions or anaphylaxis;[27,39•,41] however, 12–19% of food-induced anaphylactic reactions may require more than one dose of epinephrine.[18,32,39•,41,43] Most second doses were administered by healthcare professionals, with favorable outcomes; milk, egg, and peanuts were most common triggers and asthma was a predisposing factor.[32] Adjunctive therapies include H1-antihistamine, which may relieve skin symptoms and rhinorrhea, H2 blockers, oxygen, bronchodilators, and corticosteroids, given with the goal of preventing or ameliorating a late phase reaction although their role here has not been proven.


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