Management of Peyronie's Disease in the Aging Male

Rany Shamloul; Anthony J Bella


Aging Health. 2011;7(1):65-78. 

In This Article

Conclusion & Future Perspective

Peyronie's disease involves the development of inelastic scar of the tunica albuginea of the penis, resulting in penile deformity and sexual dysfunction. New oral medications, targeted to underlying pathophysiology, are needed to effectively treat this disorder, in addition to the rigorous testing of current candidate agents. Intralesional injection therapies provide a viable and additional minimally invasive route for patients with PD. Surgical therapy is a valuable option to restore penile morphology and improve sexual function in selected patients. At this time, there are no prognostic tests available to predict progression of disease; serum or plaque proteomics may offer potential in the future for treatment planning and disease severity stratification.[82] In the meantime, information on PD needs to be disseminated to both healthcare providers and patients, and male sexual health questions should become a standard aspect of periodic health evaluation.


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