Next-generation Sequencing and its Applications in Molecular Diagnostics

Zhenqiang Su; Baitang Ning; Hong Fang; Huixiao Hong; Roger Perkins; Weida Tong; Leming Shi


Expert Rev Mol Diagn. 2011;11(3):333-343. 

In This Article

Five-year View

In the next few years, NGS technologies are anticipated to transition into broader areas, including disease etiology, new drug development, molecular diagnostics, personalized medicine and nutrition, as well as toxicogenomics. Requisite to continuing the successful transition will be further sequencing cost reduction, improved read accuracy, more streamlined sample preparation, and perhaps more importantly, computer-based analytics for data acquisition, management, validation, analyses and biological/clinical interpretation.


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