Options for the Management of Attention Deficit/Hyperactivity (ADHD)

Marcia L. Buck, Pharm.D., FCCP, FPPAG


Pediatr Pharm. 2011;17(3) 

In This Article

Transdermal Methylphenidate

The Daytrana® transdermal patch was approved by the Food and Drug Administration in 2006.[1–3,10–12] The three layer patch consists of a polyester/ethylene vinyl acetate laminate film backing, an adhesive layer that contains methylphenidate combined with acrylic and silicone adhesives, and a protective liner that is removed prior to application. Dose varies by patch size. The patch is designed to be worn for 9 hours to provide 12 hours of symptom control, but adjustment of wear times to tailor duration remains the primary reason for selecting this formulation. The location of the patch should be changed daily to reduce skin reactions. Patients and family members must understand the need to carefully dispose of patches to prevent accidental contact or ingestion by children or pets.


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