Proton Pump Inhibitors and Severe Hypomagnesaemia

Tim Cundy; Jonathan Mackay

Disclosures

Curr Opin Gastroenterol. 2011;27(2):180-185. 

In This Article

Conclusion

Epstein et al.[7] who first reported the association of PPI use with severe hypomagnesaemia were almost certainly correct when they referred their patients as 'the tip of an iceberg'. At present, we know neither the size of the iceberg, nor why particular patients are so vulnerable to this potentially life-threatening yet readily treatable side-effect. Important questions for further research include establishing the true prevalence, understanding the risk factors and determining the mechanism whereby it develops.

Comments

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