Pistachio Diet Improves Erectile Function Parameters and Serum Lipid Profiles in Patients with Erectile Dysfunction

M Aldemir; E Okulu; S Neşelioğlu; O Erel; Ö Kayıgil


Int J Impot Res. 2011;23(1):32-38. 

In This Article


All 17 patients completed the study and none of them experienced side effects during the study. The mean age was 47.9±6.2 (range 38–59) years. Mean body mass index was 27.33±2.88 and did not change after the pistachio diet (P<0.05). Systemic systolic and diastolic blood pressure values were similar before and after the diet (P<0.05).

Before the diet, mean IIEF-5 score of the patients was 10.5±3.1. Total IIEF-15 score was 36±7.5 before the diet and 54.2±4.9 after the diet (P=0.001). Similarly, all of the five domains of IIEF-15 showed a statistically significant increase (P<0.05; Table 3 and Figure 1).

Figure 1.

Total IIEF and the five domain score findings before and after the pistachio diet. EF, erectile function; IIEF, International Index of Erectile Function; IS, sexual intercourse satisfaction; OF, orgasmic function; OS, overall satisfaction; SD, sexual desire.

Based on the results obtained from the PCDU, mean PSV of the patients was 35.5±15.2 cm s–1 before the diet and 43.3±12.4 cm s–1 after the diet (P=0.018). Although not statistically significant, the values of EDV showed an improvement after the pistachio diet (P=0.401). Other results obtained from PCDU are shown in Table 4.

After the pistachio diet, TC and LDL levels showed a significant decrease (P=0.008 and P=0.007). TC/HDL and LDL/HDL rates showed a significant decrease after the pistachio diet (P=0.001), whereas HDL level showed a significant increase after the pistachio diet (P=0.001). TG/HDL ratio showed a significant decrease after the pistachio diet (P=0.013; Table 5 and Figure 2).

Figure 2.

The improvements in lipid levels observed after the pistachio diet. HDL, high-density lipoprotein; LDL, low-density lipoprotein; TC, total cholesterol; TG, triglyceride.

Mean basal total testosterone levels were 452.1±163.4 and 379.1±95 ng dl–1 before and after the diet, respectively (P=0.030). In addition, blood platelet counts showed a significant decrease after the diet (P=0.028). Pistachio diet was not found to affect serum prolactin levels. Other biochemical variables obtained before and after the pistachio diet are shown in Table 5.


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