COMMENTARY

The Emerging Epidemic of Nonalcoholic Fatty Liver Disease

Rowen K. Zetterman, MD

Disclosures

January 21, 2011

In This Article

Summary of Key Points

NAFLD can develop in association with truncal obesity, type 2 diabetes mellitus, hyperlipidemia, and selected medications.Many patients are asymptomatic, although right upper quadrant pain may be present. End-stage liver disease can develop, and NASH is now recognized as a cause of cryptogenic cirrhosis. Therapy of NAFLD should be directed at associated conditions. Gastric bypass for obesity can improve hepatic changes in those with morbid obesity.

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