Kristina R. Burke, MD, CPT, MC, USA; George W. Turiansky, MD, COL, MC, USA


Dermatology Nursing 

In This Article


Several treatment strategies have been tried for porokeratosis with varying response. The use of sunscreens and regular observation for malignant transformation is prudent. Other treatments used include cryotherapy, CO2 laser ablation, excision, topical imiquimod, topical 5-fluorouracil with or without occlusion, topical and oral retinoids, and topical vitamin D3 analogs or combinations of the above (James, Berger, & Elston, 2006; Pierson et al., 2003). Surgical excision may be necessary if there is malignant degeneration (Montes-De-Oca-Sanchez, Tirado-Sanchez, & Garcia-Ramirez, 2006; Vergara et al., 2002). Treatment plans should be selected based on the size, number, and location of the lesions and the patient's desires.


Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.
Post as: