Xerosis is more prevalent in the winter months in the northern part of the United States due to lack of humidity. It can also be associated with eczema, psoriasis, heredity, renal disease, and diabetes. The skin presents with scale and fissures, but also might be pruritic (Draelos, 2000). Over-the-counter moisturizers are helpful for mild presentations, but prescription keratolytics such as urea and lactic acid are most effective for moderate-to-severe presentations. If the practitioner is trying to rule out tinea pedis from generalized xerosis, a KOH preparation can be performed to determine presence of a dermatophyte.
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Cite this: Foot Care from A to Z - Medscape - Sep 01, 2010.