Management of Diverticular Disease

Suzanne Albrecht, PharmD, MSLIS


US Pharmacist 

In This Article

Inflammatory Bowel Disease

There is now thought to be an overlap between chronic diverticular inflammation and the inflammation of IBD.[3] Segmental colitis associated with diverticula (SCAD) is a chronic condition occurring in the areas of the colon with diverticular formation. It is often diagnosed as ulcerative colitis or Crohn's disease; however, there are no ulcers with SCAD. The inflammation associated with SCAD typically affects the mucosa between the diverticula and not the diverticula themselves. Although IBD and SCAD share some of the same histologic changes, it is generally accepted that they are distinct clinical entities. Interestingly, patients with SCAD go on to develop IBD after resection of the affected segment of the colon. This gives rise to an "overlap" hypothesis between diverticular disease and IBD.[3]


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