Remission of Severe Restless Legs Syndrome and Periodic Limb Movements in Sleep after Bilateral Excision of Multiple Foot Neuromas: A Case Report

Ludwig A Lettau; Charles J Gudas; Thomas D Kaelin


J Med Case Reports. 2010;4(306) 

In This Article


The immediate and near-complete remission of symptoms, the histopathological documentation, and the marked improvement in polysomnographic parameters together clearly indicate that our patient's severe RLS and PLMS was of peripheral nerve (foot neuroma) origin. Further study of foot neuromas as a source of PLMS and as a cause of sleep dysfunction in patients with or without concomitant RLS, is warranted.


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