Cetirizine and Levocetirizine Use in Children

Marcia L. Buck, Pharm.D., FCCP, FPPAG


Pediatr Pharm. 2010;16(6) 

In This Article

Drug Interactions

Administration of theophylline at recommended doses may produce a small (<20%) decrease in the clearance of cetirizine. There is a possible risk for increased cetirizine serum concentrations with large doses of theophylline. Ritonavir increases serum concentrations of cetirizine by approximately 40%, slowing clearance and increasing the elimination half-life. Although not studied, the effect of these drugs on levocetirizine may be similar.[3–5]


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