Vertebral Artery Aneurysms and Cervical Arteriovenous Fistulae in Patients with Neurofibromatosis 1

Guillermo Higa; John P. Pacanowski Jr; David T. Jeck; Kaoru R. Goshima; Luis R. León Jr

Disclosures

Vascular. 2010;18(3):166-177. 

In This Article

Abstract and Introduction

Abstract

Vascular involvement in the setting of neurofibromatosis type 1(NF1) has been well described. However, the coexistence of NF1 with vertebral artery (VA) aneurysms and arteriovenous fistulae (AVFs) is a rare occurrence. A 60-year-old female with NF1 and other severe comorbidities presented with acute respiratory insufficiency caused by a ruptured large VA aneurysm and an associated AVF that required emergent intubation and eventual repair through endovascular techniques that resolved her symptoms. A detailed description of this case and a comprehensive review of the literature are also presented.

Introduction

The association between neurofibromatosis 1 (NF1) and vascular lesions has been described (Table 1 [1–15] and Table 2 [4,6,9,15–44]). Among them, the coexistence of NF1 with vertebral artery (VA) aneurysms and arteriovenous fistulae (AVF) is rare. A patient with NF1 presented with respiratory failure caused by the rupture of a VA aneurysm and an associated AVF, requiring emergent intubation and endovascular repair. A description of this case and a review of the pertinent literature are herein presented.

Comments

3090D553-9492-4563-8681-AD288FA52ACE
Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.
Post as:

processing....