Serum C-reactive Protein and Thioredoxin Levels in Subjects with Mildly Reduced Glomerular Filtration Rate

Shoko Tsuchikura; Tetsuo Shoji; Naoko Shimomura; Ryusuke Kakiya; Masanori Emoto; Hidenori Koyama; Eiji Ishimura; Masaaki Inaba; Yoshiki Nishizawa


BMC Nephrology. 2010;11:7 

In This Article


In conclusion, subjects with mildly decreased eGFR showed increased levels of biomarkers for inflammation and oxidative stress. This finding is of clinical importance, since CKD is recognized as a very high-risk population for CVD. Further studies are necessary whether the observed deviations in the biomarkers of inflammation and oxidative stress are predictive of occurrence of CVD.


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