Segmental Pigmentation Disorder

M. Hogeling; I.J. Frieden

Disclosures

The British Journal of Dermatology. 2010;162(6):1337-1341. 

In This Article

Materials and Methods

We performed a retrospective chart review of 39 patients with SegPD seen at our academic paediatric dermatology division. Patients were identified as having SegPD by searching a digital photographic archive of patients seen in the paediatric dermatology division. Of these, 18 of 39 were seen as patients during the year preceding the study when our interest in this condition was piqued. Institutional Review Board approval was obtained for the chart review. SegPD was defined as macular hyper- or hypopigmentation with a segmental (localized, unilateral, well-circumscribed, block-like patch with midline demarcation), dermatomal (area of skin supplied by a spinal nerve that is distinct from the lines of Blaschko) or 'checkerboard' (alternating squares of hyper- or hypopigmentation with sharp midline separation) pattern.[6] We excluded patients with other defined pigmentary anomalies including speckled lentiginous naevus, giant café-au-lait macules without midline demarcation, segmental neurofibromatosis, segmental vitiligo and naevoid hyper- or hypopigmentation along the narrow and broad bands of Blaschko. For each patient the following information was obtained: age, sex, age at onset of SegPD, family history, Fitzpatrick skin type, anatomical location and distribution, whether hypo- or hyperpigmented, ventral or dorsal midline demarcation, the presence of café-au-lait macules or other pigmentary abnormalities, and presence of any other skin conditions or systemic conditions or anomalies.

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