Update on Male Hormonal Contraception: Is the Vasectomy in Jeopardy?

GJ Manetti and SC Honig


Int J Impot Res. 2010;22(3):159-170. 

In This Article


In summary, male hormonal contraception is approaching the high bar set by 'the pill' and vasectomy. However, much more work is necessary to clarify the best combination therapy, timing, efficacy, and short- and long-term safety before it will reach phase 3 trials. The 10th summit meeting on Hormonal Male Contraception (2006) has agreed on the following criteria listed in Table 1 for studies on treatment modalities.[35]

Although vasectomy and condoms will likely remain very popular options, the hope for a nonsurgical treatment for male contraception will certainly remains possible in the future. Furthermore, as men's participation in the contraceptive process grows and population growth continues to represent a global concern, the demand for safer, cheaper and more reversible methods will increase as well. However, the long-term effects and male health implications of sustained hormonal supplementation remain persistent obstacles in the search for an effective and tolerable 'male pill'.


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