Chronobiology and Obesity: The Orchestra Out of Tune

Marta Garaulet; Purificación Gómez-Abellán; Juan Antonio Madrid

Disclosures

Clin Lipidology. 2010;5(2):181-188. 

In This Article

Future Perspective

Research on obesity and chronobiology is just beginning. There are still some researchers and medical doctors who are very sceptical concerning this new field. However, at present, there is widespread acceptance of the molecular clock as an important and interesting mechanism in relation to metabolism and obesity. This is illustrated by the exponential number of papers published on the subject.

Indeed, research evidence is increasing day by day. A great deal of progress has been made since the studies performed in clock gene knockout experimental models in 2005 to the epidemiological evidences and the more recent nutrigenetic studies. Our opinion is that if everything goes in the same direction, in brief, chronobiology will be crucial not only for achieving deep knowledge of the pathophysiology of obesity and MetS, but it will also be an important tool for the treatment of obesity. Different chronobiology questionnaires, genotypic analysis and the circadian measurement of physiological variables will be included in the treatment of obesity. A new view of this pathology will be reached, considering not only which are the factors implicated in obesity, but also when these factors are produced.

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