Effectiveness of Second-generation Antipsychotics: A Naturalistic, Randomized Comparison of Olanzapine, Quetiapine, Risperidone, and Ziprasidone

Erik Johnsen; Rune A Kroken; Tore Wentzel-Larsen; Hugo A Jørgensen


BMC Psychiatry. 2010;10:26 

In This Article


In this heterogeneous sample of patients acutely admitted to hospital for symptoms of psychosis, the quetiapine group was associated with the most beneficial outcome in terms of reduction of the PANSS total score; the PANSS positive subscale score; the PANSS general psychopathology subscale score; the CGI-S score; and in increasing the GAF-F score. There were no substantial differences among the SGAs regarding tolerability outcomes.