Sodium Pentosan Polysulfate Resulted in Cartilage Improvement in Knee Osteoarthritis - An Open Clinical Trial

Kenji Kumagai; Susumu Shirabe; Noriaki Miyata; Masakazu Murata; Atsushi Yamauchi; Yasuhumi Kataoka; Masami Niwa


BMC Clin Pharmacol. 2010;10:1-24. 

In This Article


This clinical treatment with pentosan for twenty knee OA patients was considered as safe with only minor AE. Improved clinical assessments were observed and degradation of collagen type II was prevented with pentosan treatment.


Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.