Recent Advances in the Treatment of Hepatocellular Carcinoma

Amit G. Singal; Jorge A. Marrero


Curr Opin Gastroenterol. 2010;26(3):189-195. 

In This Article


Despite surveillance efforts, most patients with HCC are not diagnosed at early stages when curative options are available. There have been many advances in treatment options over the past couple years for these patients, ranging from attempts to downstage tumors for liver transplantation to the introduction of targeted therapies which can prolong survival in some patients with advanced HCC. The benefit of combining systemic therapy with local treatments, such as TACE and resection, is also being investigated and holds promise for further improvements in patient outcomes. Although treatment decisions must be individualized for each patient after accounting for other factors such as degree of liver dysfunction and patient performance status, there are now possible therapies for most patients with any stage of disease.


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