Abstract and Introduction
A patient with total body epidermolytic hyperkeratosis who was successfully prescribed acitretin with the occurrence of a pyogenic granuloma is described in this case report.
Epidermolytic hyperkeratosis (EHK), also known as bullous congenital ichthyosiform erythroderma, is a rare autosomal dominant disease of the ichthyosis family with a prevalence of 1 in 300,000 people (Shwayder, 1999). Individuals affected with EHK have describable symptoms from birth. Babies suffering from EHK have a very weak top layer of skin which blisters easily. Scaling occurs due to hyperkeratosis, in which excess keratin is produced and causes a thickening of the skin. Those affected with EHK may also have incidents of ectropion, palmoplantar keratoderma, and frequent skin infections (Steele, Shea, & Petronic-Rosic, 2007). However, pyogenic granuloma is not one of the known associations.
Dermatology Nursing. 2009;21(6):345-347. © 2009 Jannetti Publications, Inc.
Cite this: Acitretin + EHK = PG: Toe Web Pyogenic Granuloma in a Man with Total Body Epidermolytic Hyperkeratosis on Acitretin – Report of A Unique Occurrence - Medscape - Nov 01, 2009.