Recognizing and Managing the Oral Clues That Point to Sjögren's Syndrome

, State University of New York at Buffalo

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Prognosis

In the great majority of SS cases, the signs and symptoms of ocular and oral dryness reach a plateau with no further progression. However, in some patients, the disease escalates and can lead to multiorgan involvement, including non-Hodgkin's lymphoma.[39] Clues to malignant transformation include a diminution of a previously elevated Ig class, persistent or greatly increased parotid swelling, generalized lymphadenopathy, and splenomegaly.[14]

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