A significantly higher percentage of premature infants with neonatal nephrocalcinosis have elevated systolic and diastolic blood pressure readings (defined as >95% percentiles of blood pressure against percentiles for length for healthy children) at 1-year and 2-year follow-up. Saarela et al. reported increases (>97.5th percentile age-specific reference) in systolic and diastolic blood pressure at 4.7 years of age (SD ± 1 year) in a small number of premature infants with and without neonatal nephrocalcinosis. Although Porter et al. report systolic hypertension in premature infants with nephrocalcinosis examined at a mean age of 6.9 years, it is not clear how systolic hypertension was defined. When effected premature infants in the Schell-Feith et al. study were followed at a mean age of 7.5 years (±1 year) and compared with preterm infants without nephrocalcinosis, there was no significant difference reported.
Pediatr Health. 2010;4(1):24-35. © 2010 Future Medicine Ltd.
Cite this: Should We Screen Preterm Infants for Nephrocalcinosis? An Evidence-based Decision - Medscape - Feb 01, 2010.