Can a Silent Kidney Infection or Genetic Predisposition Underlie Recurrent UTIs?

, University of Calgary and Alberta Children's Hospital


Medscape General Medicine. 1996;1(1) 

In This Article

Acute Urethral Syndrome

Frequency and dysuria in women may also be caused by other conditions besides a UTI, as outlined in Table II. Acute urethral syndrome is a term that has been applied to the presence of one or more typical cystitis symptoms in women who may have pyuria associated with low numbers of bacteria in urine culture (ie, usually <102 bacteria/mL). However, because most laboratories do not routinely work up low number urine cultures, they will clinically appear to have "sterile" pyuria. Stamm and colleagues[8,22] have determined that besides cystitis, acute urethritis, vaginitis, and genital herpes infections account for the remainder of cases of acute urethral syndrome. Urethral samples must be cultured or otherwise tested for these pathogens in women who are sexually active and have documented pyuria with persistently "negative" urine cultures. Urine cultures may also be falsely positive for C albicans in women with vulvovaginitis, due to urine contamination from vaginal discharge.