Low Levels of 25-hydroxyvitamin D in the Pediatric Populations: Prevalence and Clinical Outcomes

Michal L Melamed; Juhi Kumar


Pediatr Health. 2010;4(1):89-97. 

In This Article


In summary, vitamin D deficiency is a common problem worldwide. Risk factors for vitamin D deficiency include darker skin, less vitamin D intake and less outdoor activity. Low vitamin D levels can cause rickets in children, classically effecting toddlers but with increasing case reports in adolescence. Low vitamin D levels are associated with a variety of poor health outcomes including hypertension, diabetes mellitus, low bone mass, infections, dyslipidemia and asthma. The studies that suggest these associations have primarily been observational in nature and, therefore, causality cannot be established. The field needs more focus on clinical trials of vitamin D supplementation to evaluate the effects of vitamin D on the above parameters.


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