Autologous Hematopoietic Stem Cell Transplantation in Autoimmune Diseases

Claudio Annaloro; Francesco Onida; Giorgio Lambertenghi Deliliers


Expert Rev Hematol. 2009;2(6):699-715. 

In This Article

Other Indications

Disparate diseases of possible or proven immunomediated pathogenesis have been reported to be occasionally amenable to autologous HSCT. These fortuitous indications range from refractory celiac disease with T-cell dysfunction[163] to vasculitis,[127] to dermatomyositis,[164] to juvenile diabetes mellitus,[165,166] to autoimmune hepatitis and primary biliary cyrrhosis,[167] and to adult Still's disease.[168] In none of these settings have results been so favorable as to identify novel straightforward indications to autologous HSCT. On the other hand, the policy of referring to autografting severely ill patients is fully acceptable.


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