Currently Approved Prophylactic HPV Vaccines

Diane M Harper


Expert Rev Vaccines. 2009;8(12):1663-1679. 

In This Article

Duration of Vaccine Efficacy

Cost–effectiveness analyses have indicated that the vaccines must last at least 15 years or longer, or there will not be any cases of cervical cancer prevented – they will merely be postponed.[37–43] If the vaccines are given to an age group who is immediately sexually active, then despite not preventing cervical cancers, there will be some protection from the precursor lesions and a reduction in excisional treatments, which are linked to reproductive morbidity.[44,45] If the vaccines are given to the youngest ages approved, the risk of no benefit of any protection is high with a small risk of serious side effects.


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