Caffeine Intoxication and Addiction

Holly Pohler


Journal for Nurse Practitioners. 2010;6(1):49-52. 

In This Article

Management of Intoxication

Clinical management of caffeine intoxication is directed at controlling symptom presentation. An antacid of the provider's preference may improve symptoms related to gastritis. Emesis may safely be controlled with utilization of metoclopramide or ondansetron. Phenothiazine antiemetics are contraindicated because they can lower the seizure threshold, placing the patient at greater risk for seizure activity. Administration of oral diazepam or lorazepam is appropriate for symptomatic relief of agitation and anxiety. Diazepam IV 5 to 10 mg or lorazepam IV 2 to 4 mg are preferred starting doses for the treatment of seizure activity, realizing repeated doses may be necessary.[4] Sinus tachycardia is common, but typically does not require intervention. A dysrhythmia that threatens hemodynamic stability should be treated using standard advanced cardiac life support and pediatric advanced life support protocols.[4]


Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.