Toxoplasma gondii Infection and Cerebral Toxoplasmosis in HIV-infected Patients

Vera Lucia Pereira-Chioccola; José Ernesto Vidal; Chunlei Su


Future Microbiol. 2009;4(10):1363-1379. 

In This Article

Abstract and Introduction


Cerebral toxoplasmosis is a major cause of morbidity and mortality among HIV-infected patients, particularly from developing countries. This article summarizes current literature on cerebral toxoplasmosis. It focuses on: Toxoplasma gondii genetic diversity and its possible relationship with disease presentation; host responses to the parasite antigens; host immunosupression in HIV and cerebral toxoplasmosis as well as different diagnostic methods; clinical and radiological features; treatment; and the direction that studies on cerebral toxoplasmosis will likely take in the future.


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